Erectile Dysfunction (ED) is a sexual health disorder that affects millions of men globally. Due to the inability to sustain and maintain an erection, ED interferes with satisfactory sexual performance. It negatively impacts the physical and psychological health of both the partners. It deteriorates the quality of life and results in strained relationships. It is commonly seen in men aged 60 and above. However, it can occur in men of any age. The pharmaceutical market has a lot of ED medications available for men. One such highly efficacious medicine manufactured by an Indian pharmaceutical company is Kamagra 50.

What is Kamagra 50 mg?

• Kamagra 50 mg is a drug that is effectively used for the treatment of ED in men.
• It is recommended by doctors for men who have premature ejaculation and poor erection.
• It contains the active ingredient Sildenafil citrate.
• It increases the blood flow into the penis, thereby helping men affected by ED to achieve and maintain an erection for sexual intercourse.
• In addition to ED, Kamagra is also used in the treatment of Pulmonary Arterial Hypertension (PAH) and Benign Prostatic Hypertrophy (enlarged prostate).

Benefits of Kamagra 50 mg

• Effectively treats erectile dysfunction problem in men
• Boosts sexual performance and confidence in men
• Improves relationship between partners
• Enhance overall sexual wellness
• Quick onset of action

PDE5 inhibitory action of Kamagra

• Kamagra belongs to the class of PDE5 (phosphodiesterase type 5) inhibitor drugs.
• It specifically inhibits the PDE5 enzyme responsible for the inability of a man to get or maintain an erection. 
• The active ingredient ‘Sildenafil Citrate’ present in Kamagra blocks the inhibitory activity of PDE5 in degrading the cyclic guanosine monophosphate (cGMP).
• cGMP is a secondary messenger responsible for relaxation of the smooth muscles of the penis and directing blood flow to it.
• After taking Kamagra 50 mg, since there is no PDE5 blocking the cGMP action, the cGMP levels are high enough in eliciting and maintaining penile erection during sexual activity.

Working of Kamagra 50 mg

• Sildenafil citrate present in Kamagra 50 is a phosphodiesterase inhibitor.
• It prevents cyclic GMP (guanosine monophosphate) degradation by the PDE5 enzyme.
• Due to the inhibitory action of Kamagra on PDE5, the levels of cGMP increase.
• High cGMP levels cause relaxation of muscles in the penis, allowing more blood flow into it.
• Vasodilation results in better erections sexually stimulated.
• Without sexual arousal, cGMP is not activated. Hence, there will not be an erection.

Administration of Kamagra tablets

• Kamagra 50 mg tablets can be taken on an empty stomach or with a meal. 
• It should be strictly taken as advised by the medical practitioner. 
• The tablet should be taken about 1 hour before planned sex. 
• The amount of time it takes to work varies from one individual to another. 
• Generally, it takes between 30 minutes to 1 hour for the tablet to start working. However, if the person has had a heavy meal before, the onset of action takes longer.
• This medicine will only work to help a man get an erection if he is sexually stimulated.  
• The tablet should not be taken more than once a day.
• The tablet should be swallowed directly (wholly)with water. 

The person taking it must not bite, chew, or break it into pieces in the mouth.

• The effect of Kamagra lasts for about 4 to 6 hours.

Side effects of Kamagra 50 mg

Just like other ED medicines, there are some known side effects of Kamagra 50. These include:

• Headache
• Nausea
• Vomiting
• Diarrhoea
• Muscular pain
• Flushing
• Dizziness
• Nasal congestion

These side effects are mild in nature and generally disappear on their own. However, if they aggravate, the tablet must be stopped and medical attention must be sought immediately.

Precautions and warnings of Kamagra 50 mg

• Avoid alcohol consumption and grape juice while taking this medicine to reduce the side effects.
• Avoid high-fat meals as it can slow down the absorption of the medicine.
• Do not take this medication if allergic to Sildenafil or other PDE5 inhibitors.
• It is not suitable for men with severe cardiovascular, renal or liver conditions.
• Avoid combining with nitrates-based medications
• Inform the doctor about all existing medicines and health conditions.
• A person who has recently had a heart attack, stroke, or has low blood pressure should not take the medicine.
• It is not recommended for use in pregnant and breastfeeding women.
• Do not take more than one tablet in 24 hours.

Kamagra 50 mg is a widely used and preferred medicine for its ease of use, cost effectiveness, potency, and ease of use. When combined with sexual stimulation, it improves the quality of erection in men by increasing blood flow to the penis. However, this tablet should be taken only under a doctor’s guidance to ensure safety and effectiveness in ED treatment.